Skip to main content

Big dreams and nanomedicine: optical nanotransformers

Guest blogger: Elizabeth Bernhardt, a physics research assistant in nonlinear optics at Washington State University, is  blogging on presentations at SPIE Optics + Photonics in San Diego, California, 28 August through 1 September.

Dream big dreams, create amazing solutions:
Paras Prasad offered inspiration in a talk on
how nanomedicine can save lives
Treating diseases in the human body can be incredibly difficult and certain cancers may even be inoperable.

In the opening all-symposium plenary at SPIE Optics + Photonics 2016, Paras Prasad, Executive Director of the Institute for Lasers, Photonics, and Biophotonics at the University at Buffalo, New York, told how he aims to bring treatment directly to the source of the disease, using light.

Inspired early on by James Cameron's move Fantastic Voyage (1966), Dr. Prasad imagined sending something tiny into the human blood stream to specifically target disease. He turned science fiction into reality via nanomedicine.

Nanomedicine uses incredibly small devices, such as multilayered nanotransducers, to treat human diseases from inside the body. The first layer absorbs a particular wavelength of light. The next layer takes this absorbed energy and converts it to a higher or lower wavelength, which is then re-radiated.

The overarching idea is to take low-energy light, such as infrared, send it to a particular location in the body, then change the light to a different, more useful energy. IR light easily passes through the human body with very little damage. Nanotransducers absorb this light, turning it into useful, high-energy visible light, which is easily and readily absorbed by nearby cells. The cells are then destroyed, for an effective and potentially less dangerous way of treating cancer.

Dr. Prasad described another dream becoming reality, via the work of Nobel Laureate Maria Goeppert-Mayer, who developed the theory of two-photon absorption.

At the time, it was assumed experimental verification would never be possible. However, with development of the laser, two-photon absorption occurs every time one uses a green laser pointer.

Moreover, two-photon absorption can be used for dental bonding, killing bacteria, two-photon microscopy, and more. Indeed, Dr. Prasad showed materials applicable to night vision, security, and friend-foe identification. These materials appear to be different colors based on the light they absorb.

He challenged the audience to turn their own imaginings into reality as well. Perhaps the next project in optogenetics (using light to effect genes) will cure or help people with neurological disorders, or even enhance capabilities ... maybe one day neurophotonics will help Superman jump from the pages of a comic book into real-life super-human capabilities.

Note: On Wednesday 31 August, Dr. Prasad will receive the SPIE Gold Medal, the highest award of the Society, in recognition of his work.

Comments

Popular posts from this blog

#FacesofPhotonics: Rising Researcher Alina Zare

SPIE's #FacesofPhotonics is sharing the story of Alina Zare, Associate Professor at the The Machine Learning and Sensing Lab at the University of Florida. Dr. Zare was recognized as a 2018 Rising Researcher for her work in Electronic Imaging & Signal Processing, at the SPIE Defense + Commercial Sensing conference.

This program recognizes early career professionals who conduct outstanding research in the defense, commercial, and scientific sensing, imaging, optics, or related fields. If you want to learn more about the program, the details are here.

Enjoy the interview with Alina!

1. Tell us about when you first became interested in optics and photonics. In my senior year of  undergraduate studies in computer science, I was taking an Image Processing elective.  I really enjoyed the course, and the professor for the class, Dr. Gerhard Ritter, encouraged me to do some undergraduate research.  
So I joined Dr. Paul Gader's research lab as a undergraduate researcher where I he…

Lighting Their Way

It's a feast for the science-curious senses: in June, two cohorts of two dozen middle-school girls came together for the free, STEM-focused, four-day-long Physics Wonder Girls Camp sessions organized by Dr. Roberto Ramos, associate professor of physics at the University of the Sciences in Philadelphia.

The girls studied the properties of light, built telescopes, designed and engineered submersible robots, and learned about scientific professions directly from the experts: nanoscientist and Chair of Bryn Mawr College's Physics Department Dr. Xuemei Cheng; INTEL software engineer Dr. Marisa Bauza-Roman; and several female food scientists from Puratos, a global company working with bakers and chocolatiers to assess the best ways to improve their products, all came and talked about their professions, answering questions and interacting with the campers. Plus, they got to be on TV!

The camp was initially inspired by Dr. Ramos' daughter Kristiana who expressed interest in the s…

#FacesofPhotonics and Women In Optics feature: IBM Researcher Anuja De Silva

Meet the SPIE Faces of Photonics star of the week, SPIE Member Anuja De Silva. Anuja grew up in Sri Lanka and now resides in Albany, New York, where she works as a materials and process researcher in the Semiconductor Technology Research division of IBM. Speaking of her work, she says, "I develop new types of materials and processes that help us to scale the size of computer chips... It's hardware development for next-generation semiconductor devices."

Anuja graduated with her Bachelor's in Chemistry from Mount Holyoke College and went on to get her Master's and PhD in Materials Chemistry from Cornell University. Upon conducting a research project for her undergraduate degree, she found her passion for optics and materials research.


"I have always been interested in math and science," Anuja shares. "The options in Sri Lanka, where I grew up, for a career as a research scientist were limited. My mother encouraged me to apply to college in the Unite…